Population Structure of Multidrug-Resistant Klebsiella oxytoca within Hospitals across the United Kingdom and Ireland Identifies Sharing of Virulence and Resistance Genes with K. pneumoniae
نویسندگان
چکیده
oxytocawithin Hospitals across the United Kingdom and Ireland Identifies Sharing of Virulence and Resistance Genes with K. pneumoniae Danesh Moradigaravand*, Veronique Martin, Sharon J. Peacock, and Julian Parkhill* Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom British Society for Antimicrobial Chemotherapy, Griffin House, Birmingham, United Kingdom Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kingdom London School of Hygiene and Tropical Medicine, London, United Kingdom
منابع مشابه
Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland
Klebsiella pneumoniae is a human commensal and opportunistic pathogen that has become a leading causative agent of hospital-based infections over the past few decades. The emergence and global expansion of hypervirulent and multidrug-resistant (MDR) clones of K. pneumoniae have been increasingly reported in community-acquired and nosocomial infections. Despite this, the population genomics and ...
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Objective(s): Plasmid-mediated quinolone resistance (PMQR) determinants and integrons have a considerable contribution to bacterial drug resistance in Gram-negative pathogens. We studied the prevalence of PMQR genes and integron carriage in multidrug-resistant community isolates of Klebsiella spp.Materials and Methods: Two hundred and fi...
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Background: Community-acquired infections by multidrug-resistant (MDR), extended-spectrum β-lactamase (ESBL) producing Klebsiella species (Klebsiella spp.) is of major concern worldwide. Antibiotic resistance, production of extended-spectrum β-lactamases (ESBLs), and carbapenemases, as well as the presence of classes 1, 2, and 3 integrons in outpatient isolates of Klebsiella collected from Yazd...
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Background and Objective: Klebsiella pneumoniae is known as one of the opportunistic pathogens. The prevalence of antibiotic resistance, emergence of multidrug resistant strains, and multiple virulence factors contribute to the development of various infections. In this regard, the aim of this study was to evaluate the frequency of fimH, magA, and rmpA genes among Klebsiella pneumoniae isolates...
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Background & Aims: The efflux pumps play an important role in the development of drug resistance in Klebsiella pneumoniae. The aim of this study was to investigate the antibiotic resistance, and the presence of efflux genes, as well as molecular typing in clinical isolates of Klebsiella pneumoniae. Materials & Methods: In this cross sectional descriptive study, a total of 100 K. pneumoniae iso...
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